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Furthermore, a novel method using a combination of electron impact ionization (EI) and collision-induced dissociation coupled to GC/MS (GC-EI-MS) has been applied to accurately quantify the anti-aging lipid compound oleoylethanolamine (OEA) in nematodes, providing an excellent method for measuring the OEA dynamics under different genetic and environmental perturbations [232]

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It is well-documented that the microbial diversity of healthy-weight individuals is higher than that of obese individuals (67)

Therefore, future large-scale, multicenter RCTs with extended follow-up periods are urgently needed to rigorously evaluate the long-term efficacy, safety, and durability of -3 PUFAs in the PCOS population, thereby providing more robust evidence for their clinical application

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Despite these limitations, nutrient combinations appear to have promise for the management of migraine