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Description

Increased levels of ROS and lipid peroxidation products and/or decreased levels of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, and antioxidant compounds, such as glutathione, have been reported in both NAFLD/NASH patients as well as a variety of animal models of NAFLD 9,10,11,12,13,14

Goss AM, Chandler-Laney PC, Ovalle F, Goree LL, Azziz R, Desmond RA, Bates GW, Gower BA

Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

identified the expression of Wnt5a within human and mouse atherosclerotic lesions using apolipoprotein e-deficient mice and concluded that activation of the TLR-4 signaling cascade induces Wnt5a expression, and the crosstalk between TLR-4 and atypical Wnt family members, including Wnt5a, synergistically contributes to atherosclerosis

The resulting acute pulmonary edema severely impairs gas exchange, leading to profound hypoxemia, respiratory distress, and rapid death due to cardiogenic shock