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obtained a pyrazolone small molecule compound (C646) through virtual screening, which has been demonstrated to inhibit tumor proliferation, promote tumor apoptosis, alter glucose metabolism, reduce tumor drug resistance and induce tumor immune response in different kinds of cancers

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Sakkas D., Mariethoz E., Manicardi G., Bizzaro D., Bianchi P., Bianchi U

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Benificial effect of stachydrine on the traumatic brain injury induced neurodegeneration by attenuating the expressions of Akt/mTOR/PI3K and TLR4/NF-B pathway