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Acknowledgements This paper was supported by grants from the National Nature Scientific Foundation of China (No: 81770639), Construction project of advanced clinical medicine, Capital Medical University (No.1192070312) and Beijing Municipal Science & Technology Commission (No

325, Sept

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Application protocols optimized for delicate eye area The periorbital region requires modified application approaches compared to general facial peptide protocols due to extremely thin skin, high sensitivity to irritation, proximity to eyes creating contamination risk, and tendency toward product migration into eyes causing discomfort

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