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TK2 is a rate-limiting enzyme which mediates deoxypyrimidine phosphorylation ( TK2 is also involved in the maintenance of dNTP ( Encephalomyopathic Mitochondrial DNA Depletion Syndrome Encephalomyopathic is a relatively common form of MDS, in particular among adults who have progressive external eye muscle paralysis (adPEO)

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Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward

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