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Estimated glomerular filtration rate, albuminuria, and adverse outcomes: an individual-participant data meta-analysis

The difference in the nonleaving group ligand results in a structurally distinct class of DNA adducts that are repaired and recognized at different rates, contributing to a distinct spectrum of action, but the DNA lesions ultimately trigger the same cell killing pathways

Single nucleotide variations (polymorphisms) in the sequence of genes can modify gene expression level and the stability and activity of the synthesized proteins

Schlter and Drenckhahn, 1986)

One-way ANOVA
