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Mice were fed ASX supplements for 70 days, HPLC-PDA analysis showed that ASX could accumulate in both the dermis and epidermis in a dose-dependent manner, and the concentration of ASX in the dermis is ~2030 times that of the epidermis per square millimeter of skin area

Smaller molecules, which can enter the tunnels, do so and, thus, have a longer path in passing through the column

Cells were then lysed in ice-cold cytoplasm extraction reagent I (CER I) for 10 min and ice-cold CER II for 1 min

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Metabolic Engineering of Plant Secondary Metabolites: Prospects and Its Technological Challenges