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2010;21 P286 373

Kleeff, J., Korc, M., Apte, M., La Vecchia, C., Johnson, C

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G proteins mediate a wide variety of cellular functions, including, but not limited to, altering the production of second messengers such as cyclic adenosine monophosphate (cAMP), mobilizing internal calcium stores, modulating ion channel function, altering neurotransmitter release, and influencing gene expression

The N-terminal domain of ArnA then catalyzes the formylation of UDP-l-Ara4N, a critical step because only the N-formylated derivative acts as a substrate for ArnC, which transfers the moiety to undecaprenyl phosphate