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The two cytokine receptor activators of nuclear factor-B (NF-B) ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) are essential for osteoclastogenesis in vitro and in vivo [1, 7]

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Furthermore, the effects of these potential candidates on the antitumor activity of cyclophosphamide haves not been yet evaluated in either in vivo experiments or clinical trials

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Enzymes cut them, and the gut wall blocks large molecules

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