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showed that zwitterionic and neutral nanoparticles possess highly hydrated, charge-balanced surfaces that minimize serum protein adsorption, complement activation, and cytokine release (IL-6, TNF-)

Glutathione reductase plays a vital role in cellular defense against oxidative stress by maintaining high levels of reduced glutathione in the cytosol, which is essential for detoxifying reactive oxygen species and protecting cellular components from oxidative damage

Measurement of HNE-protein adducts in human plasma and serum by ELISAComparison of two primary antibodies

Ongoing research is also focusing on identifying new targets, investigating the effectiveness of combination therapies, and exploring the use of targeted radiotherapy on tumor stem cells

Iwamoto K, Bundo M, Kato T

Nature 395, 392395