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In contrast, HepG2 cells with hamster S9-mix demonstrated 100% sensitivity for the chosen carcinogenic NAs

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Spitzer RL, Terman M, Williams JBW, Terman JS, Malt UF, Singer F, et al

Masuda, T., Sugiyama, N., Tomita, M

In preclinical studies, ADI-PEG20 was reported to be effectively in suppressing cancer growth, inducing apoptosis and autophagy in different cancer types in vitro and in vivo
