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10.1016/j.bcp.2017.09.010 110 TakayanagiH

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Although the exact mechanisms of pathogenesis are yet to be elucidated, the hyper-inflammatory state in severe COVID-19 patients is believed to promote cellular damage in multiple organs including lungs (Chen et al., 2020)

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doi:10.1177/039463201202500123 138

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Noteworthy, Gustafson EK et al

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NMDA, N-methyl D-aspartate

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Experimental evidence suggests the involvement of overproduction of free radicals in the onset of diabetes and diabetic complications, with oxidative stress proposed as a pathogenic mechanism linking insulin resistance with the dysfunction of beta cells and endothelium, impaired glucose tolerance and overt diabetes

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