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Most vitamin B12 injections dont pose the risk of side effects

Hmedeh C, Ghazeeri G, Tewfik I
PSMF1/PI31 can bind to the 20S catalytic molecule of the 26S proteasome, making it difficult for the substrate to access the enzyme core and thus inhibiting the activity of the proteasomes [50]

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Conclusions This study demonstrates an up-regulation of GPX4 in neurons of substantia nigra and association of this protein with dystrophic axons in striatum of Parkinson's brain, indicating a possible neuroprotective role

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