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The clinical significance of L-carnitine in ameliorating insulin resistance (IR) lies in its intervention in a core pathogenic feature of MASLD: hepatic IR

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The required amount can also be obtained through diet or supplements, where it is found in high concentrations

10.1016/j.neuron.2017.09.020 [DOI] [PubMed] [Google Scholar] 102.Pan J, Xia J, Deng F, Liang W, Wu J, Yin B, et al

Preconditioning with soluble guanylatecyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice