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This is because flavonoids with catechol groups, such as EC and CH, lacks conjugation to the 3-OH group in C-ring which shield such molecules to form ( p )para-quinone methides, and thus, flavonoids with these structural properties restrict their oxidation at the B-ring by the tyrosinase enzyme 104

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This was due to the ability of the S

Unexpectedly, TACQ could not only induce mitophagy but also block the mitophagic flux, which was confirmed using mCherry-GFP-LC3B staining experiments

doi: 10.1093/jn/134.12.3225

This can lead to an increase in blood flow to the brain, which can cause a temporary increase in intracranial pressure and result in a headache