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Metagenome survey of biofilms in drinking-water networks

Samiec PS, Drews-Botsch C, Flagg EW, Kurtz JC, Sternberg P Jr., Reed RL, and Jones DP

This ATP depletion stimulates the degradation of ADP to AMP and inositol with the generation of xanthine and subsequently uric acid (Rosset, Surowska, & Tappy, 2016)

doi: 10.1016/j.nucmedbio.2015.07.005 74 WangQTiffenJBaileyCGLehmanMLRitchieWFazliLet al

At the molecular level, the balance of anabolic and catabolic (protein degrading) processes is coordinated primarily by the phosphoinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR)/Forkhead boxO3a (FOXO3a) pathway among others (Glass, 2005)

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