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It has been reported that five weeks of rats exposure to 1, 3, 6, and 10mg/kg/day of polystyrene nanoplastics [PS-NPs] suppress the serum level of T3, FT3, and FT4 synthesis and circulating level of thyroid hormones (41) ( Table 2 )

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Inflammation, whether occurring within the context of chronic inflammatory disease or tumor-induced inflammation, significantly influences TME composition, particularly the plasticity of tumor and stromal cells [218]