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While androgen deprivation therapy (ADT), often combined with supplementary treatments like radical prostatectomy and radiotherapy, can effectively manage and slow down the diseases progression in its early stages (Wala et al., 2023), the development of castration resistance is an inevitable outcome

Conclusion The multifaceted nature of age-associated cognitive decline calls for complex approaches that address all key factors involved in the development of neurodegenerative disorders such as oxidative stress, neuroinflammation, disrupted bioavailability of copper, impaired circulation, and altered gene expression

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