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This has even been achieved in lower eukaryotes such as Saccharomyces cerevisiae , where a significant resistance to chlorambucil and doxorubicin (eight- and 16-fold, respectively) was reported in cells transfected with mammalian GST isozymes (Black et al ., 1990)

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10.1523/JNEUROSCI.6569-10.2011 [DOI] [PMC free article] [PubMed] [Google Scholar] Qiu S., Lu Z., Levitt P

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