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Instead of a simple side-chain modification, cysteine residues can form disulfide bonds with each other

[DOI] [PMC free article] [PubMed] [Google Scholar] 394.Chang S.M., Wen P., Cloughesy T., Greenberg H., Schiff D., Conrad C., Fink K., Robins H.I., De Angelis L., Raizer J., et al

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50, 51, 52 It is also known that the adaptive response induced by 4-hydroxynonenal, one of the important determinants of oxidative stress, is positively mediated by gene expression of cyto-protective protein (Nrf2/Keap-1) pathway