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GeroScience 41 (5), 655670

This is consistent with the findings of Mehana et al

The exact cause of MS is not yet known, but oxidative stress has been strongly implicated in both the inflammatory and neurodegenerative mechanisms in the disease

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doi: 10.3389/fcimb.2025.1733264 Received 30 October 2025 Revised 25 November 2025 Accepted 29 November 2025 Published 16 December 2025 Volume 15 - 2025 Edited by Akansha Singh, University of Texas Southwestern Medical Center, United States Reviewed by Cristin Coman, National Institute of Medical-Military Research and Development, Romania Rahul Ahuja, University of Colorado, United States Updates Copyright 2025 Resta, Tal, Conte, Calcagnile, Bucci and Alifano

Cultured cells Murine cardiomyoblasts (H9c2, ATCC, CRL-1446) and primary human umbilical vein endothelial cells (HUVECs, ATCC, PCS-100-010) were evaluated in vitro