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Key messages Critical illness is characterized by severe metabolic stress and glutamine depletion has been associated with increased mortality in some recent studies

Trends Cardiovasc Med

A Note for Patients: While the benefits are clear, it is crucial to prioritize food sources over supplements

The transmembrane concentration gradients of the xCT substrates glutamate and CYS 2 limits the opportunity for direct feedback regulation, so we considered whether xCT activity might be further determined by the environmental CYS 2 concentration in cells with high SLC7A11 expression

Reproductive Toxicology., 23 (4), 578587
