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All authors collected the bibliography, wrote the first draft of the article, and developed, refined, and carefully reviewed the final version of the article

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The levels fall to about 50% by age 50 and reach just 1% by age 80
Nevertheless, due to the compensative mechanisms of the basal ganglia, thalamic nucleus, and the cerebellum, the clinical symptoms of motor deficits do not appear until 50%70% of the dopaminergic neurons in substantial nigra are impaired and the dopamine levels in the striatum are depleted by approximately 80% (George et al., 2009

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Analysis of anthocyanins in rat intestinal contents impact of anthocyanin chemical structure on fecal excretion
