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25,56,57 Activated JNK not only phosphorylates IRS-1 serine to block its proper activation, but also causes phosphorylation and translocation of FOXO1 directly (Fig

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Mishra S, Maurya VK, Kumar S, Ankita AK, Saxena SK (2020) Clinical management and therapeutic strategies for the thyroid-associated ophthalmopathy: current and future perspectives