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MiR-126 suppressed metastatic endothelial recruitment and metastatic colonization through targeting IGFBP2 in addition to PITPNC1 and MERTK genes [40]

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60 screened 16 platinum-sensitive or resistant samples from EOC patients with a reduced representation of bisulfite sequencing and detected that the upstream region of the hMSH2 gene was hypermethylated in the platinum-resistant group

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HGH binds the GHR on hepatocytes, activating the JAK2/STAT5 signaling cascade and stimulating transcription of the IGF-1 gene, producing 70% of circulating IGF-1

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