glutathione s-conjugate The role of glutathione-S-transferase in anti-cancer drug resistance Mouse Glutathione S-Transferase A1 (GSTA1)

About 5% to 10% of patients acquire early-onset PD, which onsets before 50 years old [5]

[DOI] [PMC free article] [PubMed] [Google Scholar] [24].Alam J, Camhi S, Choi AMK

This screening protects patient safety and ensures appropriate protocol design based on individual circumstances

Utiger, R

Metabolic activation of specific natural products from herbal and dietary supplements is mediated by hepatic cytochrome P450 or intestinal bacteria, and generates chemical reactive/toxic metabolites that bind to cellular reduced glutathione or macromolecules, and form reactive metabolites-glutathione/protein/DNA adducts, and these protein/DNA adducts can result in toxicities

Mehra R, et al