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Together with the fact that no clear hints for the need for rescue analgesia could be drawn from the data of the von Frey Filament tests, it is questionable whether the use of a test for skin hyperesthesia is a good choice for evaluating immediate postoperative analgesia

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In this model, LN metastasis serves as an important prognostic factor and triggers lymphadenectomy to prevent tumor cells from spreading further to distant organs (150152)

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