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The severity of the deficiency varies widely depending upon the mutation and the subunit affected
And few are more talked about than N-acetylcysteine (NAC) and Glutathione (GSH)
Microscopically, there is a diffuse process consisting of a combination of epithelial cell destruction, lymphoid cellular infiltration, and fibrosis
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doi: 10.1084/jem.20061943 124 JohnR.MathewJ.MathewA.AravindakumarC
