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Pera-Kajn J, Jakubowski H

Hydroxy cobalamin and cyanocobalamin are physiologically active after being converted to methylcobalamin or 5-deoxyadenosylcobalamin

According to a study published in PubMed Central (National Institutes of Health), intravenous administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency

Petiet, A., Aigrot, M

PubMed Park JR et al

As the pedigree depicted autosomal recessive inheritance, homozygous and compound heterozygous variants were preferred but heterozygous variants were not ignored