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The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans

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These numbers come from rodent studies scaled to a human size, not from human clinical trials

Facciol A, Visalli G, Lagan A, Di Pietro A

Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: mitohormesis for health and vitality