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Compared to growth hormone releasing peptides, it works downstream in the growth pathway, directly stimulating tissues rather than triggering natural GH release

For instance, the poor oral bioavailability of osthole is due to rapid metabolism by CYP3A4

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[9] Co-administration with glucocorticoids or adrenocorticotropic hormone may exacerbate fluid retention and oedema

Gmez-Benito M, Granado N, Garca-Sanz P, Michel A, Dumoulin M, Moratalla R

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