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3bd) confirm the reduction in SCFAs production by the microbiome and an increase in fatty acid oxidation in fasted Pcca -/- (A138T) mice

The clinical onset and progression of metabolic and neurodegenerative disorders is closely tied to aging, dysfunction in telomere processing, and the processes of cellular senescence and oxidative stress ( Table 1 )

doi: 10.1093/cvr/cvp226