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J., Mayo, J

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Overall, natural polymorphisms at positions R155 and V36 are frequent in subtype 1a, but rare in subtype 1b where substitutions at position A156 are preferentially selected in vitro [19]

Of note, because statins have been shown to significantly reduce cardiovascular events through a variety of alterations [224, 225], it is difficult to assess whether statins can affect cardiovascular outcome events through alterations in Lp(a)