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In the presence of Tg, the ATP/ADP ratio is significantly decreased only in 4 wpi nodules, indicating that the inhibition of NR partially affects the energy state in mature nodules, but not in 10 hpi and 4 dpi roots

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A notable example is the putative cation-transporting ATPase 13A2 encoded by the ATP13A2 gene, in which mutations have been linked to juvenile-onset atypical Parkinsons disease and KuforRakeb syndrome (OMIM 606693) 72,73

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Further research is needed to confirm the efficacy and safety of obinutuzumab in treating AEs