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Peer review Peer review information Nature Communications thanks Carlos Sebastian, who co-reviewed with Lisa Pltl, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Long-term use of extremely high doses could potentially disrupt kidney or liver function, especially in people with existing health conditions

These include zinc, magnesium, vitamin B6 or P-5-P, methionine, N-acetylcysteine (NAC), and creatine

doi: 10.1038/mt.2009.1

PMID: 33 RossBXChoiJYaoJHagerHMAbcouwerSFZacksDN