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These effects on inflammation and bone resorption have been demonstrated in rats with experimental periodontitis

In a study with 740 patients, tesofensine at different doses resulted in weight loss of -0.9%, -1.32%, and -2.32% compared to a slight increase in the placebo group

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doi: 10.1089/jir.2011.0065 233 McKinneyEFSmithKG

[DOI] [PubMed] [Google Scholar] 37.Park J.M., Lee H.J., Sikiric P., Hahm K.B