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JCI Insight 9 , e175159 (2024)

As detected by DCFH-DA staining, GCLC overexpression reestablished cellular ROS levels in cells expressing shACTL6A, phenotypes remained significant when treated with H 2 O 2 and was reversed by NAC (Fig

Bridging these methodological gaps will be essential for generating robust and generalizable evidence, thereby accelerating the translation of promising therapies into clinical practice

Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century

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191 Conclusions In summary, the essential role of NADPH homeostasis has been increasingly recognized in cancer development and progression through cellular antioxidative effects and anabolic reactions