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Doses above ~500 mcg/day are not generally linked to added benefit in the reference literature, and none of this reflects proven human efficacy
doi:10.2174/157340313805076322 What is AOD 9604 (3mg)
The 50100mg range appears in protocols because it approximates allometric scaling from effective rodent doses, but rigorous human pharmacokinetic data validating those numbers is sparse
Routine B12 testing is not recommended for asymptomatic individuals without risk factors
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