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ALKBH5-induced circular RNA NRIP1 promotes glycolysis in thyroid cancer cells by targeting PKM2

This disruption promotes chemokine release in HIV-infected glial cells, which in turn recruits peripheral immune cells and induces a pro-inflammatory response within glial and peripheral immune cells [162,163,164]

This disparity raises a critical question for practitioners: How can one responsibly bridge the gap between compelling mechanistic promise and the current realities of the clinical evidence

In cortex for example, astrocytes in response to diffuse injury up-regulate GFAP and become mildly hypertrophic, however they retain their territorial domain and generally do not proliferate

Broad-spectrum iron chelation, as highlighted by the 'Deferiprone Paradox', risks impairing physiological processes while attempting to block ferroptosis

From patients to platelets and back again: pharmacological approaches to glycoprotein VI, a thrilling antithrombotic target with minor bleeding risks