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These proteins function as sensors and regulators, translating ionic fluctuations into adaptive responses

Poultry Science, 99(11), 52225232

The absence of CLOCK disrupts mitochondrial turnover and the efficiency of ETC, leading to a substantial increase in ROS production [255, 256]

Li G, Chan YL, Wang B, Saad S, George J, Oliver BG, et al

In senescence microglia, lactate concentration is elevated, and IB, a negative regulator of NF-B, is phosphorylated and subsequently degraded, leading to activation of the NF-B pathway (Wei L

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