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IL-6 also utilizes gp130 to activate the PI3K-Akt pathway and the Ras-RAF-MEK-extracellular signal-regulated kinase 1/2 (ERK1/2) pathways, further enhancing inflammatory response and cell survival (151, 152)

However, it was added as an amendment during the manuscript writing phase of study execution to map the broad evidence base

[DOI] [PubMed] [Google Scholar] 3.Curtis D., Johnston G

[DOI] [PMC free article] [PubMed] [Google Scholar] 348.Gautier CA, Kitada T, and Shen J