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Using fatty acids to prolong the duration of the action of peptides and proteins was already a long established technique at Novo Nordisk and elsewhere and had been successfully applied to insulin (insulin detemir) (Knudsen, Lau)

The diversity of study subjects helps to comprehensively understand the differences in adaptability and susceptibility among various populations to high-altitude environments

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Headache 54(3):472484 Liu H, Xin T, He W, Li F, Su ZQ (2014) Myelinated Ah-type trigeminal ganglion neurons in female rats: neuroexcitability, chemosensitivity to histamine, and potential clinical impact