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Using multiple peptides simultaneously requires understanding interactions and appropriate dosing adjustments

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Phosphoproteomics using MS 3 -based tandem mass tag (TMT) reporter ion quantitation identified a total of 5,863 proteins and 17,102 phosphopeptide groups (31,372 total peptide groups) across all NQO1+ treatment groups in our phosphoproteomics dataset (Figure 2 and Supplementary Figure 3) and 4,371 proteins and 12,206 phosphopeptide groups (18,486 total peptide groups) across all treatment groups in NQO1*2 cells (Supplementary Figure 4)

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