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Periorbital study (28 days) : Palmitoyl pentapeptide-4 cream (0.005%) applied twice daily to the periorbital area decreased fold depth by 18%, fold thickness by 37%, and improved skin firmness by 21%

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10-Oxo-12(Z)-Octadecenoic Acid, a Linoleic Acid Metabolite Produced by Gut Lactic Acid Bacteria, Potently Activates PPAR and Stimulates Adipogenesis

Zhang X, Jiang J, Chen Z, et al

Gray DS, Bray GA, Bauer M, Kaplan K, Gemayel N, Wood R, et al
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