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10.3233/CBM-170142 47 HsiehY

Daily consumption of blueberries helps maintain heart health by lowering blood pressure, improving cholesterol levels, and enhancing overall cardiovascular function

: inhibition or downregulation

Polymorphism of GSTs While polymorphisms have been identified within each class of GSTs, only the heterogeneity that may contribute to variations in pathology or clinical response will be addressed in this review

We then made both single and double mutations on both of the ERE binding sites (located at 1005 and 944) in the pOXTR full length construct, and the reporter assay showed that ERE single mutants (M-1005/ERE, M-944/ERE) significantly decreased OXTR reporter activity in the LG treatment group compared to the wild type full length (pOXTR-2000/LG), while ERE double mutants (M-1005/-944/ERE) further decreased reporter activity, mimicking the reporter activity of the full length reporter construct (pOXTR-2000) in the HG treatment (see Figure 2D)
