glutamine peptides vs glutathione Frontiers difference between l glutamine and

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607 Clausenamide, an alkaloid isolated from Clausena lansium , interacts directly with Ser663 of ALOX5, blocking the nuclear translocation of ALOX5, alleviating lipid peroxide accumulation and ferroptosis in dopaminergic neurons, significantly improving behavioral deficits in PD mouse models, and providing an attractive strategy for PD treatment

Using gene knockouts together with transcriptomic and metabolomic profiling, we identified an important shift in redox balance due to GR deficiency, which disrupted energy metabolism and weakened the oxidative stress defense, culminating in a notable decline in virulence

Chan LKM, Braidy N, Ng W, Xu YH, Chen J, McDonald R

This study aims to investigate the involvement and the mechanism underlying alcohol-induced ferroptosis and the role of miRNAs in regulating ferroptosis sensitivity

Liu X, Cai Y, Zhang Y, Zhang H, Tian S, Gong Y, et al