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used the rat pancreatic beta cell line Rin-5F to induce cell death via DM mimics, including high glucose, H 2 O 2 , and STZ, and reported that these factors accumulate ROS and iron, inactivate NRF2, and reduce the mitochondrial membrane potential, while treatment with Fer-1 mitigated these effects [87]

1986 Aug;61(2):402-8

[DOI] [PMC free article] [PubMed] [Google Scholar] 702.Wang, G

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Induction of thoracic aortic dissection: a mini-review of -aminopropionitrile-related mouse models
