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Furthermore, the MR analysis framework employed in this study serves as a valuable model for further explorations into the underlying aetiology and mechanisms driving SLE

doi: 10.1136/annrheumdis-2019-216515 150 van VulpenLFDHolsteinKMartinoliC

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These proteases exist as inactive zymogens and require proteolytic cleavage to become enzymatically active

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