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doi: 10.1038/nri.2016.70, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 19

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While computational approaches aimed at predicting such interactions exist, at least in the case of lifespan modulation they remain to be experimentally validated 13

PLPP1, PLPP2, and PLPP3 possess six transmembrane spanning domains that allow then to be localized to the plasma membrane, membranes of the endoplasmic reticulum (ER), and membranes of the Golgi

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