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Gupta P, Kim B, Kim SH, Srivastava SK

To neutralize ROS, cells induce various antioxidant systems, including the activation of the protein machinery that produces glutathione [10], the most abundant antioxidant scavenger in all cells [11, 12]

Its mechanism involves activating the AMPK/SIRT1 pathways and suppressing lipogenic regulators like PPAR and SREBP-1c, highlighting its potential as a therapeutic candidate for NAFLD (96)

Futur J Pharm Sci 10 , 106 (2024)

SAT1 is a transcriptional target of P53 and an important rate-limiting enzyme for polyamine catabolism

doi: 10.1016/j.redox.2017.03.007 99 PaulB
